Top 50 Nfl Rushing Leaders All Time 2025 Rushing. These are the most accomplished nfl rushing leaders of all time, who dedicated their body and careers to securing first downs. Surpassed 100 tackles all eight of his nfl seasons.
Between the 2020 and 2025 seasons, derrick henry rushed for the most yards, with 6,789 yards. Surpassed 100 tackles all eight of his nfl seasons.